刘炎,教授,博士生导师。中国神经科学学会再生与发育生物学会委员,江苏省细胞与发育生物学会常务理事。先后入选江苏省高校“青蓝工程”中青年学术带头人、“江苏省333高层次人才”等人才项目。
研究方向及成果:再生分子机制。通过比较生物学的方法,探讨不同物种、不同个体发育阶段及不同组织器官再生能力的差异及可能的机制,尤其关注再生过程中干细胞的性质及行为特点。作为主持人承担国家自然科学基金、江苏省自然科学基金、江苏省高校自然科学重大项目等课题,以通讯作者或第一作者在Nature Communication, Journal of biological chemistry等高水平期刊发表论文,并作为第一完成人获得教育部高等学校科学研究优秀成果二等奖。 邮箱:liuyan@ntu.edu.cn
代表性论文:
1: Guan T, Guo B, Zhang W, Qi M, Luo X, Li Z, Zhang Y, Bao T, Xu M, Liu M*, Liu Y*. The activation of gastric inhibitory peptide/gastric inhibitory peptide receptor axis via sonic hedgehog signaling promotes the bridging of gapped nerves in sciatic nerve injury. J Neurochem. 2023 Mar 27. doi: 10.1111/jnc.15816.
2: Dong Z, He W, Lin G, Chen X, Cao S, Guan T, Sun Y, Zhang Y, Qi M, Guo B, Zhou Z, Zhuo R, Wu R, Liu M*, Liu Y*. Histone acetyltransferase KAT2A modulates neural stem cell differentiation and proliferation by inducing degradation of the transcription factor PAX6. J Biol Chem. 2023 ;299(3):103020. (Selected as Editors’ Pick)
3: Ma C, Wang J, Tu Q, Wu R, Lai X, Lin G, Dong Z, Guan T, Qiang L, Liu Y*, Liu M*. Fidgetin impacts axonal growth and branching in a local mTOR signal dependent manner. Exp Neurol. 2023; 361:114315.
4: Wang Q, Mao Z, Liu Z, Xu M, Huang S, Wang Y, Xu Y, Qi L, Liu M, Liu Y*. Akt/mTOR integrate energy metabolism with Wnt signal to influence wound epithelium growth in Gekko Japonicus. Commun Biol. 2022;5(1):1018.
5: Ma C, Teng L, Lin G, Guo B, Zhuo R, Qian X, Guan T, Wu R, Liu Y*, Liu M*. L-leucine promotes axonal outgrowth and regeneration via mTOR activation. FASEB J. 2021 ;35(5):e21526.
6: Fang S, Xu M, Teng L, Lv Y, Yang J, Mao Z, Wang Y, He W, Wu R, Liu M, Liu Y*. Comparison of neural stem/progenitor cells from adult Gecko japonicus and mouse spinal cords. Exp Cell Res. 2020;388(1):111812.
7: Liu Y, Zhou Q, Wang Y, Luo L, Yang J, Yang L, Liu M, Li Y, Qian T, Zheng Y, Li M, Li J, Gu Y, Han Z, Xu M, Wang Y, Zhu C, Yu B, Yang Y, Ding F, Jiang J, Yang H, Gu X. Gekko japonicus genome reveals evolution of adhesive toe pads and tail regeneration. Nat Commun. 2015 ;6:10033.