高永静,神经生物学专业博士,博士研究生导师,教授,航海医学研究所副所长,江苏特聘教授。在SCI收录的期刊上发表论文近40多篇,主持完成多项国家自然科学基金、江苏省自然科学基金和江苏省高校自然科学研究计划项目。先后入选教育部新世纪优秀人才支持计划、江苏省“333”工程第三层次人才、江苏特聘教授。目前担任中华医学会疼痛学分会基础组委员会委员、中华医学会航海医学分会青年副主任委员、中国神经科学会感觉和运动分会委员、胶质细胞分会委员、江苏省疼痛学会委员、南通市疼痛学会副主任委员。担任国家自然科学基金项目青年基金项目和面上项目函审专家,担任疼痛和神经科学领域30多种国际专业杂志审稿专家。
研究方向:神经损伤引起慢性疼痛的机制
近三年主要通讯作者论文
1. Bao-Chun Jiang, De-Li Cao, Xin Zhang, Zhi-Jun Zhang, Li-Na He, Chun-Hua Li, Wen-Wen Zhang, Xiao-Bo Wu, Temugin Berta, Ru-Rong Ji, Yong-Jing Gao*. CXCL13 drives spinal astrocyte activation and neuropathic pain via CXCR5. Journal of Clinical Investigation. Accepted.
2. Bao-Chun Jiang, Wen-Xing Sun, Li-Na He, De-Li Cao, Zhi-Jun Zhang, Yong-Jing Gao*. Identification of lncRNA expression profile in the spinal cord of mice following spinal nerve ligation-induced neuropathic pain. Mol Pain. 2015 Jul 17;11(1):43.
3. Jun-Jie Chen, Lin Dai, Lin-Xia Zhao, Xiang Zhu, Su Cao, Yong-Jing Gao*. Intrathecal curcumin attenuates pain hypersensitivity and decreases spinal neuroinflammation in rat model of monoarthritis. Scientific Reports. 2015 May 19;5:10278.
4. Yan Shen, Zhi-Jun Zhang,Ming-Di Zhu,Bao-Chun Jiang, Tian Yang, Yong-Jing Gao*. Exogenous induction of HO-1 alleviates vincristine-induced neuropathic pain by reducing spinal glial activation in mice. Neurobiology of Disease. 2015 Jul;79:100-10
5. Ying Lu, De-Li Cao, Bao-Chun Jiang, Tian Yang, Yong-Jing Gao*. MicroRNA-146a-5p attenuates neuropathic pain via suppressing TRAF6 signaling in the spinal cord. Brain, Behavior, and Immunity. 2015 Oct;49:119-29
6. Ying Lu, Bao-Chun Jiang, De-Li Cao, Zhi-Jun Zhang, Xin Zhang, Ru-Rong Ji, Yong-Jing Gao*. TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-a and IL-1b signaling. Pain. 2014 Dec;155(12):2618-29
7. De-Li Cao, Zhi-Jun Zhang, Rou-Gang Xie, Bao-Chun Jiang, Ru-Rong Ji, Yong-Jing Gao*. Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2. Experimental Neurology. 2014 May 20;261C:328-336
8. Xiang Zhu, Su Cao, Ming-Di Zhu, Jin-Qian Liu, Jun-Jie Chen, Yong-Jing Gao*. Contribution of chemokine CCL2/CCR2 signaling in the dorsal root ganglion and spinal cord to the maintenance of neuropathic pain in a rat model of lumbar disc herniation. Journal of Pain. 2014, May; 15(5): 516-526
9. Lin-Xia Zhao, Bao-Chun Jiang, Xiao-Bo Wu, De-Li Cao, Yong-Jing Gao*. Ligustilide attenuates inflammatory pain via inhibition of NFkB-mediated chemokines production in spinal astrocytes. European Journal of Neuroscience. 2014, Apr; 39(8):1391-1402
10. Jie Xu, Ming-Di Zhu, Xin Zhang, Hao Tian, Jin-Hua Zhang, Xiao-Bo Wu, Yong-Jing Gao*. NFkappaB-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice. Journal of Neuroinflammation. 2014 Mar 1;11(1):38
11. Zhi-Jun Zhang, De-Li Cao, Xin Zhang, Ru-Rong Ji, Yong-Jing Gao*. Chemokine contribution to neuropathic pain via respective spinal cord induction of CXCL1 in astrocytes and its receptor CXCR2 in neurons. Pain, 2013,Oct;154(10):2185-97
12. Ying Lu, Lin-Xia Zhao, De-Li Cao, Yong-Jing Gao*. Spinal injection of docosahexaenoic acid attenuates carrageenan-induced inflammatory pain through inhibition of microglia-mediated neuroinflammation in the spinal cord. Neuroscience, 2013,Mar 14, 241C:22-31
13. Jie Hui, Zhi-Jun Zhang, Xin Zhang, Yan Shen, Yong-Jing Gao*. Repetitive hyperbaric oxygen treatment attenuates complete Freunds adjuvant-induced pain and reduces glia-mediated neuroinflammation in the spinal cord. Journal of Pain, 2013, May 14, 14(7):747-758